As another of period of dusk begins, in a region of the world where people are beginning to live humble lives once again… This land lacks the system of a governed nation, yet people live together, hand in hand. There, in an isolated workshop, lives a girl who makes a living by making medicine. This girl's name is Ayesha. She used to live with her grandfather and younger sister, but after her grandfather passed away a few years ago, her sister also went missing. Now she is only left with her pet cow, and her solitude.

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Atelier Ayesha: The Alchemist of Dusk